Antiplasmodial and larvicidal flavonoids from Derris trifoliata

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Antiplasmodial and Larvicidal Flavonoids from Derris Trifoliata

From the dichloromethane-methanol (1:1) extract of the seed pods of Derris trifoliata, a new flavanone derivative (S)-lupinifolin 4 -́methyl ether was isolated. In addition, the known flavonoids lupinifolin and rotenone were identified. The structures were determined on the basis of spectroscopic evidence. Lupinfolin showed moderate in vitro antiplasmodial activity against the D6 (chloroquine-se...

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A new prenylated flavanone from Derris trifoliata Lour.

A new flavanone, 4',5,7-trihydroxy-6,8-di-(2-hydroxy-3-methylbut-3-enyl)- flavanone, was isolated from the aerial parts of Derris trifoliate, together with eleven known compounds: rotenone, tephrosin, 12a-hydroxyrotenone, deguelin, 6a,12a-dehydro-rotenone, dehydrodeguelin, 7a-O-methyldeguelol, 7a-O-methylelliptonol, 5,7,3',4'-tetra-hydroxy-6,8-diprenylisoflavone, daidzein and 4'-hydroxy-7-metho...

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Isolation and Characterization of Leaf Extract of Derris Trifoliata

Derris trifoliata belongs to the family Fabaceae of the order Papilionoideae. D. trifoliata is used in local medicine in India as a stimulant, antispasmodic and counter-irritant, and against rheumatism, chronic paralysis and dysmenorrhoea. The bioactive principle present in the leaves of Derris trifoliata was isolated and characterized in the present study. The powdered leaves were repeatedly e...

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Potent Antiplasmodial Alkaloids and Flavonoids from Dasymaschalon acuminatum

A new aporphine alkaloid, 7-epi-duguetine (1) together with one known alkaloid, dicentrinone (2), and four known flavonoids, quercetin 3,7-dimethyl ether 3′-O-α-L-rhamnopyranosyl-(12)-β-D-glucopyranoside (3), galangin 5-methyl ether (4), 5,7-dimethoxy-3-hydroxyflavone (5), and 3,5,7-trimethoxyflavone (6), were isolated from the leaves of Dasymaschalon acuminatum, a new plant species which has ...

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Anti-Angiogenic Activity of Rotenoids from the Stems of Derris trifoliata.

The plants in the genus Derris have proven to be a rich source of rotenoids, of which cytotoxic effect against cancer cells seem to be pronounced. However, their effect on angiogenesis playing a crucial role in both cancer growth and metastasis has been seldom investigated. This study aimed at investigating the effect of the eight rotenoids (1: -8: ) isolated from Derris trifoliata stems on thr...

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ژورنال

عنوان ژورنال: Bulletin of the Chemical Society of Ethiopia

سال: 2009

ISSN: 1011-3924

DOI: 10.4314/bcse.v23i3.47665